Clinical Applications

These tests are seldom used in routine clinical assessment of stable patients. In acute respiratory failure, mouth occlusion pressure during unstimulated breathing may be of value in assessing respiratory drive and the likelihood of successful weaning.

occlusion pressure has no proven clinical value in respiratory muscle disease but may occasionally be helpful by pointing to an unsuspected mechanical problem.

If a patient is known to have a mixed problem of muscle weakness and a lung disease (e.g., polymyositis plus interstitial pulmonary fibrosis) and the response of the controller to Co2 or o2 is being studied, P0.1 can be measured in conjunction with ventilation as the response and may be a more reliable way of comparing the result with normal values.

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