1. Beginner and long-limbed individuals should include more unilateral work to fully stimulate their HTMUs while also including bilateral work for every muscle group to correct the bilateral deficit. In other words the beginner wants to correct his bilateral deficit but while he does so, he should include more unilateral work to still be able to stimulate as much growth as possible.
2. As an individual gains more experience, his CNS will become more efficient at recruiting the HTMUs and as a result his bilateral deficit will decrease. They can increase the amount of bilateral and decrease unilateral work (while still keeping it in the program).
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.