There are several drugs prescribed by doctors for individuals with insulin insensitivity such as diabetics. Athletes had realized these drugs had a re-partitioning effect upon the muscle-to-fat ratio in favor of muscle gain and fat loss.
Additionally, the drugs acted to increase muscle cell insulin receptor-site sensitivity and number while they decreased fat cell sensitivity. The result was a decrease in dosages used for insulin during protocols and a return to progress for the athletes. Insulin "efficiency" was the actual goal.
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