Increases in height velocity from baseline values were less in children receiving sermorelin than in those receiving somatropin in 2 studies. Patients were randomised to receive subcutaneous sermorelin (30 ug/kg/day by constant infusion pump delivering a pulse every 24 minutes or as 3 divided doses) or subcutaneous somatropin 30 ug/kg once daily for 6 months in these trials.
The recommended regimen of sermorelin (30 ug/kg once daily) has not yet been directly compared with once daily somatropin, although sermorelin was given at the correct daily dosage.
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