Example 4 Chart

DAY

DRUGS

1.

Remeron 7.5mg/Aromasin 25mg

2.

Remeron 7.5mq/Aromasin 25mq

3.

Remeron 15mg/Aromasin 25mg

4.

Remeron 15mg/Aromasin 25mg

5.

Remeron 15mg/Aromasin 25mg

6.

Remeron 15mg/Aromasin 25mg

7.

Remeron 15mg/Aromasin 25mg/HCC 1000iu

8.

Remeron 15mg/Aromasin 25mg

9.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

10.

Remeron 15mg/Aromasin 25mg

11.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

12.

Remeron 15mg/Aromasin 25mg

13.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

14.

Remeron 15mg/Aromasin 25mg

15.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

16.

Remeron 15mg/Aromasin 25mg

17.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

18.

Remeron 15mg/Aromasin 25mg

19.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

20.

Remeron 15mg/Aromasin 25mg

21.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

22.

Remeron 15mg/Aromasin 25mg

23.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

24.

Remeron 15mg/Aromasin 25mg

25.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

26.

Remeron 15mg/Aromasin 25mg

27.

Remeron 15mg/Aromasin 25mg/HCG 1000iu

28.

Remeron 15mg/Aromasin 25mg

Remeron (mirtazapine) tablets are prescribed as an antidepressant. Before thoughts of Frank on Prozac spin in your head realize that this is a section on cortisol and estrogen control.

Mirtazapine (Remeron) lowers cortisol and prolactin in normal subjects (like athletes are ever normal?) This appeared to an effectual alternative to Cytadren for those interested in lowering cortisol levels. It also lowers prolactin resulting in a decrease in fatty tissue and HPTA inhibition.

Additionally there was a mild (low dose) antidepressant effect as well that some welcomed post-cycle. Kind of like low dose Prozac, Cytadren and bromocriptine or cabergoline all in one. It is noteworthy that many have reported improved appetite during Remeron use, but several have also reported sleeping 12 hours the first few days of use even with the stepped initial dosages.

In studies 15mg/d resulted in a significant decrease in cortisol. What is really interesting is the method of inhibition. ATCH is a hormone that tells the adrenal glands to release corticoid steroids. Naturally most are catabolic to protein tissue (like muscle). However the suppression of ATCH leads to less cortisol being produced without inhibition of sex steroid synthesis.

This means a significant increase potential for LH/FSH production and the resulting increase in natural androgen production. Yup, that is right. Remeron inhibits ATCH secretion. Of course the anti-prolactin effect is nice in the bedroom as well.

Endocrinological effects of mirtazapine in healthy volunteers.

Prog Neuropsychopharmacol Biol Psychiatry 2002 Dec;26(7-8):1253-61

OUR FRIEND ESTROGEN ...AND ITS EVIL COUSINS

So far I have made a sincere effort to avoid techno-geek stuff for the most part. However, it seems paramount at this point to include some that was not included in "Chemical Muscle Enhancement". Frank gets pretty bored during techno-geek discussions. I, on the other hand, am amazed at the human body.

Estrogen is not a single function, single form or structure hormone. Most bodybuilders assume estrogen is the stuff that gives women great racks and weird (but fun) mood swings. Or they view estrogen as only an evil hormone that makes males bloated, soft, and gyno prone. Did you know a males woody would be a wood-have-been without estrogen? How about estrogens IGF-1 stimulating and glucose transport mediating properties explained earlier?

The term "estrogen" is a catch-all term utilized to describe a group of biologically active hormones. Just as most doctors and the media have grouped all AAS into one single term, so have most abused the word estrogen.

"So, Frank. You wonder at the power of propaganda? You have a point. As to most doctors and the media grouping all AAS into one group, try this on for size: "Arguments must therefore be crude, clear and forcible, and appeal to emotions and instincts, not the intellect. Truth was unimportant and entirely subordinate to tactics and psychology." Sound familiar? The quote was from Joseph Goebbeles and his thoughts on WW II. Created perception is all that matters to most. A few think for themselves before they act. In that lies success" CoXM^b

*Think about that and read on.

The amounts and ratios vary or differ for men and women, but the body produces several different estrogens. 4-Hydroxyestrone, 2a-Hydroxyestrone, 16a-Hydroxy estrone, estrone, estriol, and 17b estradiol for example. Each has different metabolic pathways for production and each has a different level of estrogenic activity. This means that the body has a purpose for each estrogen and some are stronger than others.

1 7b-estradiol is the most powerful estrogen and has strong estrogenic effects upon tissue. 1 7b-estradiol can convert or metabolize into estrone, which in turn can convert into 2a-hydroxyestrone, and/or 16a-hydroxyestrone. This conversion process is mediated by enzymes. In fact, in some cases, the enzymes the body uses to convert androgens (Such as androstenedione and Androstenediol) into stronger hormones (Such as testosterone) can also effect estrogen production. Obviously the body needs a balance of all hormones and hormone-like substances. This of course means that alterations made through chemical muscle enhancements can have a non-synergistic effect if not properly structured.

Several studies have shown that the ratio of 2a-Hydroxyestrone to 16a-Hydroxyestrone is a deciding factor in the development of estrogen related tissue and cancer. For this reason the medical community is utilizing Nolvadex, Arimidex, Aromasin, Faslodex and others as a treatment for, and prevention of, breast cancer.

In rare cases, male gynecomastia has developed into full-blown breast cancer so readers be aware. Research strongly suggests that a higher level of 2a-Hydroxyestrone and lower level of 16a-Hydroxyestrone is beneficial for prevention.

Estrogen control protocols have been described in depth in "Chemical Muscle Enhancement" and in the present text. Most of these examples utilized drugs that were prescription only in many countries.

However there are a few studies that support the use of OTC products to effectively control estrogen to a respectable degree. Di-indoly-methane (DIM), lndol-3-carbinol (1-3-C), lycopene, and ground flax seed (And flax seed oil) have studies supporting their beneficial effects upon decreasing bad estrogens while increasing the good.

DIM and 1-3-C both potentially aid in estrogen deactivation and evacuation. They do so by inhibiting the conversion enzyme responsible for 16a-Hydroxyestrone formation. This then forces the body to utilize the C-2 pathway and increase the production of 2a-Hydroxyestrone. The body then excretes the inactive metabolite of 2a-Hydroxyestrone rather quickly and effectively. This results in less total circulatory estrogens as well.

The good side of AAS aromatization for Frank was the fact that estrogen passing through the liver increases the production and release of IGF-1. Estrogen also positively affects the hypothalamus-pituitary-axis only in that it triggers the release of GH.

As you know by now, IGF-1 triggers the up-regulation of satellite-cell production, and the newly formed cells (In the presence of elevated androgen levels) possess a higher number of androgen receptor-sites (Meaning that the new cells potentially have a higher capacity to respond to AAS)

Since IGF-1 also increases the inclusion of satellite-cells into both existing and newly formed muscle fibers, growth potential is further enhanced. Theoretically, by aiding in a better 2a-Hydroxyestrone - to - 16a-Hydroxyestrone ratio, and the subsequent conversion to and excretion of 2-Methoxyestrone at a faster rate, more IGF-1 would be produced. So the use of DIM and 1-3-C before, during, and after AAS cycles did have interesting benefits. I believe this may have been true for both sexes.

Personal experience has shown that the inclusion of DIM, 1-3-C, and flax seed powder or oil is surprisingly effective during high estrogen level periods for any athlete. In addition their inclusion during phases such as Absolute Anabolic Phases has had a certain synergistic effect.

500mg/d DIM, 500mg/d 1-3-C, and up to 3 tablespoons of flax seed oil per day has been effective for several athletes employing low dosage AAS protocols.

Turbo Metabolism

Turbo Metabolism

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