What Happens After Testosterone Molecules Leave Receptors

After a testosterone (or AAS) molecule has bonded with an androgen receptor-site and delivered its message, it returns to the blood stream. It can either contact other receptor-sites and do it all again, or it can be changed by enzymic reactions into other compounds such as estrogen, androstenediol, etc., or converted into ineffective molecules which are then excreted though urine. The testosterone molecule can also be converted into DHT (dihydrotestosterone). DHT has a higher affinity (attraction) to receptor-sites than testosterone. DHT has strong androgenic characteristics and weak anabolic qualities for the most part. In fact, DHT is about 5-times as androgenic as testosterone. It also loves sebaceous glands, hair follicles, and prostate tissue. This means more acne and oily skin, hair loss on the scalp, and potential growth of prostate tissue if there is an excess of estrogen and the 5-LO enzyme present. The good news is that DHT improves muscle hardness and cannot be aromatized to estrogen. Regardless of type or derivative, all steroid molecules are processed by the liver and hit the toilet eventually.

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