Reported Characteristics

Active Life: about 8-12 hours

Drug Class: Synthetic estrogen/HPTA stimulator (Oral)

Average Reported Dosage: Men 50-100 mg daily

Water Retention: No

High Blood Pressure: Rare

Aromatization: None

Liver Toxic: Low, seldom reported.

Strong gonadotropin stimulator/mild anti-estrogen

Clomiphene is a synthetic estrogen clinically administered to help women ovulate. Bodybuilders, (male) following AAS cycles, seeking to jump start natural testosterone production (or those that were simply seeking a natural testosterone spike) have used this drug with great success. Clomiphene increases activity in the hypothalamus-pituitary-gonadol axis by stimulating the release of more gondotropin from the pituitary gland. Therefore, a higher/faster level of LH (luteinizing hormone) and FSH (follicle stimulating hormone) results. This creates a signal to the leydig cells in the testes which in turn produce more testosterone and sperm. Normally with Clomiphene this took 5-15 days. Most started with 50-mg twice daily for about 5 days, then reduced intake to 50 mg once a day for 5-10 more days. Due to Clomiphene providing a fast response time, I felt it was often beneficial to use a dosage of 100 mg total daily for 5 days, mid-cycle during longer AAS protocols. This drug was seldom utilized for longer than 15 days continuously simply due to it being unnecessary. The goal was to normalize testosterone production post AAS cycle as quickly as possible so as to minimize post-cycle strength and mass loss. Not create dependency.

HCG was combined with Clomiphene (Clomid) sometimes, or Clomiphene was used after HCG administration. This is because Clomiphene acts by affecting the hypothalamus and pituitary (hypophysis) and regenerating the whole regulating system, while HCG only "imitates" LH, thus stimulating the leydig cells in the testes to produce natural testosterone. (*Also see HCG)

*Some may wonder about Clomiphene being a synthetic estrogen. Yes, it is, but it works as an anti-estrogen. This is due to the fact that Clomiphene has a very low estrogenic effect. This means stronger and more active estrogen, such as those formed during the aromatization of many androgenic steroids, are blocked out of the receptor-site and less estrogenic activity results; less gyno, less water retention. Clomiphene was by no means as effective as Novladex or Proviron for estrogen suppression, but post-cycle it helped greatly.

TRADE NAMES

ARDOMON 50 MG TABS CLOMIFEN 50MG TABS

CLOMID 50 MG TABS CLOMIFEN 25MG CAPS

CLOMIPHEN-MERCK 50MG TABS OMNIFIN 50 MG TABS

CLOSTIBEGYT 50MG TABS TOKORMON 50MG TABS

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