Loop Diuretics

Loop diuretics such as furosemide and ethacrynic acid are actually double trouble. They have a two level approach to ridding the body of endogenous water. First they act upon the kidneys like Thiazide diuretics to stimulate urine production. Obviously, this can result in excessive loss of sodium chloride, bicarbonate, and potassium as well. Second, loop diuretics negatively affect an area of the kidneys called the "Loop of Henle". This double action places a severe strain on kidneys already dealing with high dosages of certain anabolic/androgenic steroids and below normal water insertion as in a pre-contest period. These are probably the most dangerous diuretic drugs. But use was restricted to 1-3 days in most cases. Common brands of loop diuretics are Lasix and Bumex.

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