Phosphorylation of Heat Shock Proteins

Low molecular weight heat schock proteins are phosphorylated in smooth muscle: A 27-28-kDa protein is phosphorylated in various intact smooth muscles and smooth muscle cells (reviewed in Barany and Barany, (1996c). Cyclic nucleotide-dependent vasorelaxation is associated with the phosphorylation of a 20-kDa heat shock protein, called HSP20 (Beal et al., 1997; Rembold et al., 2000). It was found that HSP20 is an actin-associated protein (Brophy et al.,1999; Rembold et al. 2000) suggesting that smooth muscle relaxation may be brought about by the binding of the phosphorylated HSP20 to the actin filaments.

Was this article helpful?

0 0
Staying Relaxed

Staying Relaxed

Start unlocking your hidden power with self hypnosis by relaxing and staying relaxed. This is just the audio you have been looking for to do just this.

Get My Free MP3 Audio

Post a comment