The Action Potential Voltageclamp Experiments

The Voltage Clamp 85

Measuring Changes in Membrane Ionic Conductance Using the

Voltage Clamp 87 The Squid Giant Axon 90 Ionic Currents Across an Axon Membrane Under Voltage Clamp 90

The Gated Ion Channel Model 94 Membrane Potential and Peak Ionic Conductance 94 Kinetics of the Change in Ionic Conductance Following a

Step Depolarization 97 Sodium Inactivation 101 The Temporal Behavior of Sodium and Potassium

Conductance 105 Gating Currents 107 Summary 108

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