Cyclo Histidyl-Proline Diketopiperazine (CHP) is a naturally occurring cyclic peptide that acts as an appetite suppressant. Levels of CHP in the blood have been shown to be a strong indicator of appetite (Battaini & Peterkofsky 1980), and high levels correspond with a small appetite.
CHP has also been demonstrated to have an effect on food preference (Antelman, et al 1975), and helps to turn off cravings for fatty foods. CHP may have implications for people trying to lose weight if used correctly, and in turn this may have implications for the dieting bodybuilder. Unfortunately, yet again, there are no conclusive studies showing the direct effect of CHP supplementation on weight control.
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